2015, Vol. 1 Issue 3, Part A
Comparative evaluation of erythrocyte superoxide dismutase levels in chronic periodontitis patients before and after periodontal therapy
AUTHOR(S): Angel Fenol, Tessa Paul P, Jayachandran P, Rajesh Vyloppillil, Anuradha Bhaskar, Sai Megha Menon
ABSTRACT:Background: Only a few studies have examined the association between periodontitis and erythrocyte superoxide dismutase level. The aim of this study was to compare erythrocyte superoxide dismutase levels in subjects with and without periodontitis, before and after non-surgical periodontal therapy. Methods: This comparative study was done on subjects ≥30 to ≤60 years old. Group A consisted of 20 subjects without periodontitis, and Group B consisted of 20 subjects with periodontitis. Body mass indexes (BMI) and clinical parameters, including oral hygiene index-simplified (OHI-S), gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), haemoglobin level and erythrocyte superoxide dismutase level, of all subjects were recorded. All subjects received non-surgical periodontal therapy (scaling and root planing). After three months, all subjects were reexamined and clinical parameters and erythrocyte SOD levels were evaluated and compared with the baseline values. Results: There were significant differences between Group A and Group B in regard to baseline levels of OHI-S, GI, PPD, and erythrocyte SOD (p<0.05). There was no clinical attachment loss in Group A, either at baseline or after three months. At the end of three months, Group B showed improvement in all clinical parameters (p<0.05), and their erythrocyte superoxide dismutase levels also significantly increased (p<0.05), although the values never reached those without periodontitis. Conclusion: The erythrocyte superoxide Dismutase levels of subjects with periodontitis (Group B) significantly increased three months after non-surgical periodontal therapy, although they never reached the same level as that of the subjects without periodontitis (Group A).
Pages: 08-14 | 872 Views 1 Downloads
How to cite this article:
Angel Fenol, Tessa Paul P, Jayachandran P, Rajesh Vyloppillil, Anuradha Bhaskar, Sai Megha Menon. Comparative evaluation of erythrocyte superoxide dismutase levels in chronic periodontitis patients before and after periodontal therapy. International Journal of Applied Dental Sciences. 2015; 1(3): 08-14.