Materials and Methods: 30 peak lesion cases that achieved on 28 patients. The sample was randomly divided into two groups. Group I: Practice plasma rich platlets on 14 patients after extraction of cyst lesion. Group II: Extracted of cyst lesion for 14 patients without adding plasma rich platlets. Cases were clinically and radio graphically follow-up after 3, 6 and 9 months.

Results: PRP group showed bone reconstruction faster than the control group. There are statistical differences between groups in 1, 3, 6 and 9 months after surgery for management with PRP.

Conclusion: The results of this study suggest that using platelets rich plasma (PRP) provide bone reconstruction faster and better after eradication of maxillofacial cysts.