Aim: Present study aims to compare the flexural strength of 2 commercially available, heat-polymerized acrylic denture base materials (DPI and Trevlon).

Materials and Methods: Fifteen specimens of ISO specified dimensions are prepared for both the experimental groups 30 dental stone molds were prepared using brass metal dies of ISO specified dimensions. All samples were tested for flexural strength according to ISO specification 1657 with the use of a three point loading apparatus in the universal testing machine at a crosshead speed of 5 mm/min.

Results and Discussion: The mean flexural strength of conventional heat polymerized acrylic resin DPI Group - A was found to be 76.52 + 5.423125 MPa The mean flexural strength of unreinforced conventional heat polymerized acrylic resin Trevalon Group - D was found to be 109.56+ 7.558231MPa There was a significant difference between the flexural strength of the two commercially available PMMA.

Conclusion: Within the limitations of this in vitro study the following conclusions can be drawn: 1.There exists a marked difference between flexural strength properties of the two commercially available PMMA. 2. There is a need to make informed evidence based choices in selection of denture base materials in clinical practice.