Methods: Total of 400 questionnaires were distributed among interns and clinical students at Riyadh Elm University. The questionnaire comprised 32 items assessing infection control practices, and the data were tabulated and analyzed by SPSS to produce descriptive statistics.

Results: Three hundred nine questionnaires were answered (response rate 77%). The implementation of different infection control measures was good to excellent, except for hepatitis B vaccination and wearing eye protection: only (76%) of males and (83%) of females were vaccinated against HBV, and only (30%) of males and (26%) of females always wore protective glasses.

Conclusion: Compared to previous studies, an increased awareness regarding infection control practices among dental students and interns was noticeable. However, greater emphasis on the importance of infection control, especially compliance with HBV vaccination and wearing protective eyewear, is necessary.