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International Journal of Applied Dental Sciences
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ISSN Print: 2394-7489, ISSN Online: 2394-7497
ICV 2018: 74.52

International Journal of Applied Dental Sciences

2019, Vol. 5 Issue 3, Part C

Influence of Treponema denticola on apical periodontitis due to infection of endodontal origin

AUTHOR(S): Anali Roman Montalvo, Lizeth Edith Quintanilla Rodriguez, Nemesio Elizondo Garza, Karen Melissa Garcia Chavez, Arturo Santoy Lozano, Jose Elizondo Elizondo, Jovany Emanuel Hernandez Elizondo, Sergio Eduardo Nakagoshi Cepeda and Juan Manuel Solis Soto
ABSTRACT:Introduction: The ultimate goal of endodontic therapy is to eliminate all pathogenic bacteria from the root canal system in order to prevent apical periodontitis.
Aim: Review of literature on the influence of Treponema denticola on apical periodontitis due to infection of endodontal origin.
Methodology: Search was carried out in the database PubMed and EBSCO.
Results: T. denticola is one of the most frequently identified microorganisms within the root canals and these spirochetes are partly responsible for the pathogenesis of periapical bone lesions such as apical periodontitis. They are found within the biofilm and their aggressiveness is due to a diversity of virulence factors, highlighting their dentillisin, mobility and their ability to modulate the host's defensive response.
Conclusion: T. denticola has a series of molecular determinants that could allow it to cause tissue damage and evade the host immune response. In addition, it has several virulence determinants that allow it to promote disease progression.
Pages: 172-175  |  154 Views  23 Downloads
How to cite this article:
Anali Roman Montalvo, Lizeth Edith Quintanilla Rodriguez, Nemesio Elizondo Garza, Karen Melissa Garcia Chavez, Arturo Santoy Lozano, Jose Elizondo Elizondo, Jovany Emanuel Hernandez Elizondo, Sergio Eduardo Nakagoshi Cepeda and Juan Manuel Solis Soto. Influence of Treponema denticola on apical periodontitis due to infection of endodontal origin. International Journal of Applied Dental Sciences. 2019; 5(3): 172-175.
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