Material and method: Forty extracted single canal mandibular premolars were selected. Access cavities were prepared and the root canals were subjected to biomechanical preparation. TAP was placed into the canals until the material extruded through the apex. Volumetric analysis was performed using CBCT. The samples were randomly divided into four groups on the basis of irrigants (saline, 3% sodium hypochlorite, 17% EDTA, 0.5% peracetic acid) and sonic activation in each group used for removal.. A second CBCT was done and the volume of remaining material in each tooth was estimated as before. Volumetric analysis and percentage difference was calculated and statistically analysed using ANOVA and post-hoc test. All the experimental irrigants failed to remove TAP completely from root canals. 0.5% peracetic acid (remaining volume was 43.6) showed better removal efficacy than others. Conclusion: Combination of 0.5% peracetic acid and sonic activation results in lower amount of TAP remnants compared to other groups.