Materials and Methods: The present in vitro study was conducted on 60 heat-cure acrylic denture base resin material specimens. The specimens were divided into three groups. Group I specimens were immersed in distilled water, group II in denture cleanser and group III in thyme essential oil. The flexural strength was measured.

Results: The mean flexural strength in group I was 83.2 MPa, in group II was 89.5 MPa and in group III was 91.5 MPa. The difference was significant (P< 0.05).

Conclusion: Authors found that thyme essential oil showed better flexural strength than combination method and can be effectively used as denture cleanser.