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International Journal of Applied Dental Sciences
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ISSN Print: 2394-7489, ISSN Online: 2394-7497
ICV 2018: 74.52

International Journal of Applied Dental Sciences

2020, Vol. 6 Issue 3, Part G

Effect of 2% quercetin gel subgingival application after scaling and root planing on IL-6 concentration of chronic periodontitis patients

AUTHOR(S): Mega Sibarani, Rini Nasution, Syafruddin Ilyas, Irma Ervina and Ameta Primasari
ABSTRACT:Quercetin is an anti-inflammatory substance that possesses strong anti-inflammatory capacities through reduction of proinflammatory cytokines. Interleukin-6 is a proinflammatory cytokine produced locally in inflammatory tissue after lipopolysaccharides and other cytokines activation. The research analyzed effect of 2% quercetin gel subgingival application after scaling and root planing on IL-6 concentration of chronic periodontitis patients. It used 2% quercetin gel after scaling and root planing and 0,2% chlorhexidine gel as control. Sample was divided into 3 groups, quercetin gel group, control group (chlorhexidine gel and without gel). Gingival crevicular fluid was taken before and after treatments in each group then IL-6 examination was performed. This research used pretest-posttest control group design. There was significant difference (p<0,05) on the IL-6 concentration reduction before and after 2% quercetin gel application. Quercetin gel application reduced IL-6 concentration in gingival crevicular fluid of periodontitis patients.
Pages: 463-466  |  44 Views  5 Downloads
How to cite this article:
Mega Sibarani, Rini Nasution, Syafruddin Ilyas, Irma Ervina and Ameta Primasari. Effect of 2% quercetin gel subgingival application after scaling and root planing on IL-6 concentration of chronic periodontitis patients. International Journal of Applied Dental Sciences. 2020; 6(3): 463-466.
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International Journal of Applied Dental Sciences