Home      Online Submission      Contact Us
International Journal of Applied Dental Sciences
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
ISSN Print: 2394-7489, ISSN Online: 2394-7497
ICV 2018: 74.52

International Journal of Applied Dental Sciences

2015, Vol. 1 Issue 5, Part A

Resolvins, A powerful resolution mediator: Review

AUTHOR(S): Dr. Maheaswari Rajendran, Dr. Nirmmal Maria T, Dr. Usha R
ABSTRACT:
Resolvins are endogenous lipid derived mediators generated by the host to regulate resolution of inflammation. They are biosynthesized from dietary fatty acid specifically omega 3 fatty acids. There are two major types of resolvins, E series and D series resolvins. Resolvins control the duration and magnitude of inflammation. They act as anti-inflammatory and proresolution mediators and decrease the tissue accumulation of neutrophils. As resolvins regulate recruitment of neutrophils and macrophages to the inflamed site, they show protective effect in inflammatory diseases like colitis, acute lung inflammation, periodontitis etc. Experiments in animals and humans suggest a new approach for the control of inflammation in these diseases without compromising the host defense.
Pages: 13-18  |  925 Views  3 Downloads
How to cite this article:
Dr. Maheaswari Rajendran, Dr. Nirmmal Maria T, Dr. Usha R. Resolvins, A powerful resolution mediator: Review. Int J Appl Dent Sci 2015;1(5):13-18.
Call for book chapter
International Journal of Applied Dental Sciences