Vol. 3, Issue 4, Part F (2017)

Abstract: Recurrent aphthous stomatitis is the most common oral mucosal disorder and its etiology is multifactorial but still not clear. Most of the recent articles underline that the immunological factors play an important role in the etiopathogenesis of recurrent aphthous stomatitis (RAS). Nicotine can prevent the occurrence of RAS modulating the expression of pro-inflammatory and anti-inflammatory cytokines. There is evidence that autoimmune disease are related to RAS as autoimmune thyroiditis. This case report is a description of a rare clinical condition of recurrent aphthous stomatitis in a patient suffer from hypotiroidism.