Vol. 4, Issue 3, Part A (2018)

Abstract: Platelet rich fibrin (PRF), an autologous leukocyte is ideal biomaterial for pulp-dentin complex regeneration. It contains various growth factors like platelet-derived growth factor, transforming growth factor-1 and vascular endothelial growth factors. Their sustain release over prolonged period in root canal increases the success of revascularisation in blunderbuss canal. This case report presents 2 cases of immature apices with necrotic pulp in maxillary anterior region of young and middle age patients. After thorough disinfection of root canal with sodium hypochlorite as irrigant and triple antibiotic paste as medicament, bleeding was induced from periapical area. PRF was placed in canal as scaffold. Narrowing of apical foramen was reported in both cases after 12 months.