Home      Online Submission      Contact Us
International Journal of Applied Dental Sciences
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
ISSN Print: 2394-7489, ISSN Online: 2394-7497
ICV 2018: 74.52

International Journal of Applied Dental Sciences

2020, Vol. 6 Issue 1, Part A

A prospective, randomized, double-blinded, cross over comparison of buffered versus non-buffered 2% lidocaine with 1:80,000 adrenaline for dental extraction

AUTHOR(S): Indu Palanivel, Karthik Ramakrishnan, Vivek Narayanan, Saravanan Chandran and Prashanthi Gurram
ABSTRACT:Aim: To compare pain during injection, onset of anesthesia and effectiveness of anesthesia using buffered versus non- buffered 2% lidocaine with 1:80,000 adrenaline in dental extraction.
Patients and Methods: The investigator implemented a prospective, randomized, double-blinded, cross over study. The sample was composed of 200 extractions on 100 patients who needed bilateral extraction on same jaw. The predictable variable was buffered 2% lidocaine with 1:80,000 adrenaline and plain 2% lidocaine with 1:80,000 adrenaline. 100 patients on one side of the jaw received buffered and on the other side received plain or non buffered 2% lidocaine with adrenaline according to random number table. The outcome variable was pain during injection, onset of anesthesia and effectiveness of anesthesia on buffered and non-buffered group. Descriptive and bivariate statistics were computed and the P value was significant at 0.05.
Results: The sample was composed of 200 extractions on 100 patients. The mean pain score and efficacy of effectiveness was significantly significant in buffered when compared with non buffered 2% lidocaine with adrenaline. No significant difference was found in the onset of anesthesia between buffered and non buffered group.
Conclusion: The results of this study suggest that addition of sodium bicarbonate as a buffering agent with 2% lignocaine and 1:80,000 adrenaline reduces pain felt by the patient during injection of local anesthetics thus providing comfort to the patient. It also maintains the efficacy of effectiveness till the end of the procedure without supplemental injection.
Pages: 35-38  |  198 Views  9 Downloads
How to cite this article:
Indu Palanivel, Karthik Ramakrishnan, Vivek Narayanan, Saravanan Chandran, Prashanthi Gurram. A prospective, randomized, double-blinded, cross over comparison of buffered versus non-buffered 2% lidocaine with 1:80,000 adrenaline for dental extraction. Int J Appl Dent Sci 2020;6(1):35-38.
Call for book chapter
International Journal of Applied Dental Sciences