International Journal of Applied Dental Sciences
2020, Vol. 6 Issue 2, Part A
Comparative evaluation of alpha amylase levels in serum and saliva of healthy individuals and subjects with chronic periodontitis
AUTHOR(S): Pooja Bharadwaj, Veena Kalburgi and N Sai Sri Harsha
Introduction: Amylase is a key protein secreted in saliva and serum as a part of oral host immune response in periodontal disease. However very few documents are available on serum and salivary alpha amylase levels correlating the periodontal status in same patients. Hence to evaluate and compare the levels of alpha amylase in serum and saliva between chronic periodontitis and healthy patients.
Material and Methods: In this cross-sectional study, serum and saliva was collected from 40 patients between 25-60 years of age. They were divided into two groups Both the groups were evaluated for serum and salivary alpha amylase and clinical parameters were recorded
Results: The result of this study showed that salivary alpha amylase was significantly higher in chronic periodontitis group as compared to healthy control group. Serum alpha amylase was equally prevalent in both the groups.
Conclusion: There was an increase in salivary alpha amylase levels in chronic periodontitis patients as compared to the healthy group but the serum alpha amylase level was constant in both the groups. Thus present results have documented that salivary alpha amylase can be used as a biomarker to link new emerging diagnostic technique with novel therapeutic approach.
Pages: 15-18 | 412 Views 21 Downloads
How to cite this article:
Pooja Bharadwaj, Veena Kalburgi, N Sai Sri Harsha. Comparative evaluation of alpha amylase levels in serum and saliva of healthy individuals and subjects with chronic periodontitis. Int J Appl Dent Sci 2020;6(2):15-18.