International Journal of Applied Dental Sciences
2020, Vol. 6 Issue 2, Part C
Estimation of serum level of Vitamin A and E in OSMF patients
AUTHOR(S): Amit Jain, Gagandeep Kaur, Rajiv Ranjan, Divya Singh, Divya Porwal and Arpana Shekhawat
ABSTRACT:Background & Objectives:
Oral submucous fibrosis is a common precancerous condition. The primary factor considered in the etiogenesis of OSMF is the habitual use of betel nut. Hence this study is carried out to estimate the serum vitamin A and vitamin E levels in OSMF patients and to compare with the healthy controls.
Methods: A case control study was conducted on 60 cases of OSMF and 60 controls. The serum vitamin A and vitamin E of all 120 participants were estimated by using spectrophotometer.
Results: The mean Vit A value in the patient group was calculated to be 24.30 μg/dl where as in the control group it was 30.36 μg/dl. Comparing the values between different stages, there was a gradual reduction in the Vit A levels as the stage advanced. The mean Vit E value in the patient group was 6.03 μg/dl which was marginally lower than the mean Vit E levels in the control group 9.03 μg/dl. Comparing the values between different stages, there were almost similar values of the Vit E levels across all the stages.
Interpretation & Conclusion: The serum levels of vitamin A and vitamin E between subjects with OSMF and the healthy controls did not show any significant difference when statistically evaluated. Nor was there any considerable difference across different stages of the disease.
Pages: 174-176 | 222 Views 19 Downloads
How to cite this article:
Amit Jain, Gagandeep Kaur, Rajiv Ranjan, Divya Singh, Divya Porwal, Arpana Shekhawat. Estimation of serum level of Vitamin A and E in OSMF patients. Int J Appl Dent Sci 2020;6(2):174-176.