Review Method: An extensive electronic search for in vitro Randomized control trials and Clinical control trials via Medline (via PubMed), The Cochrane Controlled Clinical Trials Register databases up to date 3/11/2018 was done. Articles were retrieved and exported to Mendeley Desktop 1.13.3 software.

Results: In total, 18 articles were selected for review out of 102 articles retrieved from the search and remaining were excluded based on the eligibility criteria. Majority of articles (more than 90%) pointed out towards better laser induced remineralization effect compared to control group (fluoride therapy and other non-fluoride remineralizing agents) Laser therapy using Low level and Hard tissue lasers (CO₂, Er: YAG, Er, Cr: YSGG, Nd: YAG and diodes) demonstrated efficient enamel remineralization in vitro.

Conclusion: Used in conjunction with or as a replacement for conventional enamel remineralization methods, Laser induced enamel remineralization seems to have a promising future.