International Journal of Applied Dental Sciences
2020, Vol. 6 Issue 3, Part B
Evaluation of calprotectin levels in crevicular fluid from implant sites in patients with peri-implantitis
AUTHOR(S): Dr. Pallavi Kalia, Dr. Saleeta Mushtaq, Dr. Sumit Kumar Sharma, Dr. Priyanka Sharma and Dr. Priya Kaushal
Background: Peri-implantitis are also chronic inflammatory diseases associated with the accumulation of a pathogenic biofilm on the implant surface. Calprotectin is a calcium- and zinc-binding protein, which for practical purposes can be considered to be neutrophil-specific, although low levels are found in other phagocytic cells. Hence; the present study was conducted for evaluating the calprotectin levels in cervicular fluid from implant sites in patients with peri-implantitis.
Materials & Methods: A total of 10 patients with clinical and radiographic confirmed diagnosis of peri-implantitis and 10 healthy controls were enrolled. Complete demographic and clinical details of all the patients were obtained. Peri-implant crevicular fluid (PICF) sampling and sample preparation PICF samples were collected from peri-implant sites using sterile paper strips. Calprotectin in PICF samples was determined using Calprotectin Human ELISA. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software.
Results: Mean levels of calprotectin in peri-implantitis patients and in healthy controls was 204.82 ng/μL and 115.36ng/μL respectively. Significant results were obtained while comparing the mean calprotectin levels in between the two study groups.
Conclusions: Calprotectin levels in crevicular ﬂuid are significantly altered in patients with peri-implantitis highlighting their role in the pathogenesis of the disease.
Pages: 109-111 | 164 Views 10 Downloads
How to cite this article:
Dr. Pallavi Kalia, Dr. Saleeta Mushtaq, Dr. Sumit Kumar Sharma, Dr. Priyanka Sharma, Dr. Priya Kaushal. Evaluation of calprotectin levels in crevicular fluid from implant sites in patients with peri-implantitis. Int J Appl Dent Sci 2020;6(3):109-111.