International Journal of Applied Dental Sciences
2020, Vol. 6 Issue 3, Part D
Evaluation of postoperative pain management after impacted third molar surgery with preoperative oral lamotrigine: An observational study
AUTHOR(S): Dr. Atul Singh, Dr. Sanjeev Vaid and Dr. Arun Prasad
Extraction of the impacted third molar is often associated with severe postoperative pains, management of which are a big challenge. Lamotrigine is a new antiepileptic drug with pre-emptive analgesic properties, which is hypothesized to alleviate postoperative pain.
Aim of study: This study aimed to evaluate the efficacy of pre-operative administration of single oral 200 mg lamotrigine in reducing the postoperative pain of impacted third molar surgery.
Materials and Method: In this randomized controlled trial, 80 adult patients were divided into two groups (n= 40) to receive either 200 mg oral lamotrigine for 1 hour before the removal of impacted third molar. The patients were monitored for 4 hours in the recovery room and pain intensity was measured through visual analogue scale (VAS) for the next 12 hours at 30-minute intervals. The time and number of rescue analgesics used in 12 hours was also recorded.
Results: Two groups were not statistically significantly different regarding the severity of postoperative pain. (p= 0.523)
Conclusion: Accordingly, pre-emptive administration of lamotrigine was not effective in diminishing the postoperative acute pain of impacted third molar extraction
Pages: 274-277 | 247 Views 6 Downloads
How to cite this article:
Dr. Atul Singh, Dr. Sanjeev Vaid, Dr. Arun Prasad. Evaluation of postoperative pain management after impacted third molar surgery with preoperative oral lamotrigine: An observational study. Int J Appl Dent Sci 2020;6(3):274-277.