Objective: To evaluate the literature about SARS-CoV-2 from an odontological point of view.

Methodology: Using the keywords "COVID-19", "transmission routes", "serology", "diagnosis", "treatment", and "oral manifestations", the MEDLINE/PubMed and Science Direct databases were searched, from 2010 to 2020, with emphasis on the last 5 years. It was evaluated with the PRISMA and AMSTAR-2 guidelines. Results: The main transmission routes of the COVID-19 are direct contact, drops and air routes, and indirect one, fomite materials. Serological tests are complementary to molecular diagnosis in symptomatic patients, with their respective reservation, since false positives and negatives have been observed. The COVID-19 diagnosis could be made with saliva, since the salivary glands are the first affected by the SARS-CoV virus. So far, there is no specific treatment for COVID-19. Among the most important oral manifestations are anosmia, ageusia, and intraparotid lymphadenitis, which leads to a clinical picture similar to parotitis.

Conclusions: Information reviewed herein should be considered by the dentist in his daily practice, in order to reduce the risks of infection due to the frequent production of aerosol and the constant presence of saliva.