Study Design: Forty-five teeth were selected and stratified to receive either 38% SDF; 38% SDF + KI or 38% SDF + 20% GSH. The analysis for staining (DE) was done using a UV- Vis Spectrophotometer and was recorded at different intervals for one month. Data analysis was done using Kruskal- Wallis test, Post-hoc analysis (Dunn) anda repeat-measures analysis of variance (RM-ANOVA).

Results: SDF caused maximum staining. SDF + KI staining was significantly less (P<0.05) compared to SDF at 1 week, 2 weeks and one month. SDF + GSH showed least staining at 5 minutes and 24 hours among the three groups but the staining increased gradually and had no statistical difference after 1 week, 2 weeks and one month when compared to other groups.

Conclusion: Application of KI following SDF helps in reducing the staining. Addition of GSH had no significant effect.