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International Journal of Applied Dental Sciences
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ISSN Print: 2394-7489, ISSN Online: 2394-7497
ICV 2019: 92.11

International Journal of Applied Dental Sciences

2021, Vol. 7 Issue 4, Part A

Autologous platelet concentrates in regenerative endodontic treatment

AUTHOR(S): Astrid Aimee Huidobro-Guerrero, Arturo Santoy-Lozano, Fanny Lopez-Martinez, Rosa Alicia Garcia-Jau, Aurea Elizabeth Valle-Urias, Sergio Eduardo Nakagoshi-Cepeda and Juan Manuel Solis-Soto
ABSTRACT:Introduction: Autologous platelet concentrates, have recently emerged as a possible tool to improve regenerative procedures in the medical field.
Objective: To analyze the literature on autologous platelet concentrates in regenerative endodontics, such as: Platelet Rich Plasma, Platelet Rich Fibrin, PRP/PRF Vs Blood Clot as a scaffold in regenerative endodontics.
Methodology: Using the keywords Regenerative Endodontic Treatment, Autologous Platelet Concentrates, Immature Teeth, Platelet-rich Fibrin, Platelet-rich Plasma, Revitalization Endodontics, the MEDLINE/PubMed and ScienceDirect databases were searched, with emphasis on the last 5 years. It was evaluated with the PRISMA and AMSTAR-2 guidelines.
Results: Platelet-rich plasma releases growth factors during the first hours after placement and induction of mesenchymal stem cells. Platelet Rich Fibrin is a second-generation platelet concentrate that releases growth factors more slowly, forming a network that traps leukocytes and platelets, liquid platelet rich fibrin has a higher concentration of leukocytes, which enhances immune defense in LPS-induced inflammation. Compared to blood clot, PRP and PRF show improved healing results, reducing infection and inflammation.
Conclusion: The use of autologous platelet concentrates presents a more controlled scaffold in regenerative endodontics, with successful results, such as periapical healing, root thickening and apical closure.
Pages: 20-24  |  331 Views  38 Downloads
How to cite this article:
Astrid Aimee Huidobro-Guerrero, Arturo Santoy-Lozano, Fanny Lopez-Martinez, Rosa Alicia Garcia-Jau, Aurea Elizabeth Valle-Urias, Sergio Eduardo Nakagoshi-Cepeda, Juan Manuel Solis-Soto. Autologous platelet concentrates in regenerative endodontic treatment. Int J Appl Dent Sci 2021;7(4):20-24. DOI: https://doi.org/10.22271/oral.2021.v7.i4a.1347
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International Journal of Applied Dental Sciences