The human immunodeficiency virus (HIV) is a retrovirus that breaks down the body's immune system leaving the patient vulnerable to a series of life-threatening opportunistic infections, neurological disorders or unusual diseases and neoplasms.

Objective: To evaluate the information available about the human immunodeficiency virus related to its affections in the cavity. The topics to be evaluated are epidemiology, diagnosis, treatment and oral manifestations.

Methodology: In order to carry out this literature review, an electronic search was necessary using PUBMED and Google Scholar with the words "HIV AND dentistry" "epidemiology, diagnosis and treatment" and "oral manifestations ".

Results: Its incidence worldwide is 38 million people with a high incidence rate in Africa and the European Union. Its diagnosis is by serological tests and rapid IgG tests. The treatment is Antiretroviral. Its most common oral manifestations are: Kaposi's sarcoma (KS), followed by oral candidiasis, periodontitis, necrotizing ulcerative gingivitis (NUG), necrotizing ulcerative periodontitis (NUP) and oral hairy leukoplakia (OHL).

Conclusion: Dentists must know the most common oral manifestations of HIV since there is a high incidence of people infected with this virus who present in dental consultation.