Introduction: Craniofacial clefts are the result of disruption of the normal developmental program during embryogenesis affecting the face, skull or both.
Objective: To analyze the literature on oblique facial clefting, highlighting the different subtopics such as its etiology and prevalence, clinical manifestations, diagnosis, treatment and dental management.
Methodology: Articles published in databases such as PubMed, SCOPUS and Google Scholar were analyzed, with emphasis on the last 5 years. This was done using keywords such as "oblique facial cleft", with the subtopics "etiology", "oral management", "diagnosis", "epidemiology" and "treatment".
Results: The oblique facial cleft is one of the rarest forms, its incidence is believed to be in the range of 0.24% of all facial clefts. Its etiology is embryologically a failure of the lateral and maxillary process along the naso-optic sulcus. Its clinical manifestations are very variable, but a cleft can be found originating from the Cupid’s bow and can involve the alveolus between the lateral and canine, passing laterally from the medial piriform opening to the infraorbital foramen and ending in the lower orbit. Diagnosis is made in the 2nd and 3rd trimester, based on sagittal, coronal and axial views of the fetus. Treatment is based on the protection of vision and corneas, in addition to creating an adequate rehabilitation.
Conclusion: As it is a manifestation that involves the oral region, a dental team is required to complete its general treatment.