Background: Third molar impaction is a prevalent condition that affects a substantial percentage of the global population, with a global prevalence ranging from 16.7% to 68.6%. 2. Nearly half of impacted third molars are associated with some form of pathology.

Aim: To ascertain the prevalence of third molars that have been impacted in the large Tripoli, Libyan population, in relation to the level of eruption, the angulation of impaction, their accompanying pathologies, and associated demographic data (sex and age of the patients).

Material and Methods: The 8860 digital panoramic radiographs (PRs) from the large Tripoli city population were obtained retrospectively for the current investigation. Using Microsoft Excel, the sampled PRs were assessed, and the information gathered was collated and examined (Microsoft Office 2013). The data was examined using the Chi-Square analysis technique.

Results: A total sample of 8860 digital panoramic radiograph, 2077 (23.4%) cases of impacted third molars to show at least one impacted third molar. The prevalence of impacted third molars was found significantly higher in the twenties and thirties age groups (35.1%).A total of 2077 digital PRS were diagnosed with impacted third molars out of which 642 (31%) were associated with pathologies.

Conclusion: This study's sample of impacted third molars demonstrated a low frequency in the large Tripoli population. Males are more prone than females to have an impaction. The most prevalent impaction patterns were mesioangular angulation, level C impaction, and class II impaction. The enlargement of the periodontal ligament space was one of the most frequent related hard tissue diseases.