Materials & Methods: A total of 50 children of age 7-10 years, with a treatment plan of extraction of primary teeth were enrolled in the study. They were divided into 2 groups as N₂O-O₂ and oxygen. Those who presented with clinical conditions contraindicating the use of N₂O–O₂ or having known allergy to lignocaine were excluded from the study. Data was collected and result was analysed using SPSS software. The level of significance was at p≤0.05.

Results: A total of 50 children were enrolled, 25 in each group. There was a significantly lower pain reaction to local anesthetic administration in the N₂O-O ₂ group (p<0.01). Scoring was done. In O₂ administrated patients, 84% were in deep sedation during and even after the procedure. In N₂O-O_2, 32% patients were in light sedation after the procedure whereas 20% were in light sedation during the procedure.

Conclusion: N₂O-O₂ inhalation showed better results as vital signs were normal and treatment completed successfully.