The fabrication of an obturator prosthesis is crucial for the closure of partial Maxillectomy defects caused by Post COVID Mucormycosis as it improves speech, appearance, acceptability due to better mastication without nasal regurgitation, and overall health status and quality of life for the patient. Patients who cannot undergo fixed prosthetic rehabilitation using implants may benefit from attachment retained obturator prostheses. It offers the prosthesis optimal retention, stability, and support. This case report concludes that attachment retained CAD CAM fabricated obturator prosthesis improves retention, excellent aesthetics, provide good adaptation of cast partial framework with adjacent structures and light weight of prosthesis enhances acceptability of prosthesis by patient.