Background: Regardless of gender or age, simple dentures are still the first option for tooth replacement in cases of edentulousness due to the expanding sex difference in oral health and disease.

Aims: Our purpose of this research Gender analysis of patients from Benghazi who had removable dentures, their age range, significance of tooth loss in these individuals, while also considering the demands of various patient sorts for these dentures.

Materials and Methods: A retrospective-longitudinal study of Patient’s data records from two of Benghazi’s major institutions of 1708 edentulous (Partial or complete), Libyan cases who require removable complete dentures were assessed between March 15, 2014, and September 15, 2022.

Results: According to the chi-square test, Dentures had been worn by 1107 Libyan men and 601 Libyan women, most common age were fifties in both genders, but age of edentulous cases begun from 26 years, there was a Strong distinctions of reasons tooth lost, gender and kinds of dentures.

Conclusion: This study shows that Edentulism generally affects Males more than Females in city of Benghazi and it usually manifests in young, there is a major problem within Libyan community to encouragement of oral health, in addition there were a clear difference between gender, age, tooth lost, types of dental prosthesis and places.