Vol. 10, Issue 3, Part E (2024)

Floating-Harbor Syndrome (FHS) is an extremely rare genetic disorder marked by a distinctive triad: short stature, speech delay, and unique facial features such as a triangular face, bulbous nose, wide columella, deep-set eyes, long eyelashes, thin lips, short philtrum, and broad mouth. With approximately 50 documented cases, FHS poses significant diagnostic challenges due to its unfamiliar clinical presentation, often leading to delays in diagnosis. Although the syndrome affects both sexes, it is more prevalent in females, and no known cure exists—treatment remains symptomatic and supportive. Early diagnosis is crucial for prompt intervention and comprehensive management. Oral manifestation of FHS often involves oligodontia, ankyloglossia, and delayed tooth eruption, which can significantly impact oral function, appearance, and quality of life. The syndrome's characteristic facial features may complicate orthodontic evaluations and treatments. Effective management requires a multidisciplinary approach, integrating paediatric dentistry, orthodontics, prosthodontics, and surgical interventions tailored to the individual’s needs. Paediatric dentists & oral radiologists play a key role in early detection and management, employing thorough dental evaluations and panoramic radiographs for timely intervention. A deep understanding of the syndrome’s dental manifestations and potential complications is essential for optimal treatment planning and patient outcomes. Continued research and collaboration with geneticists and other healthcare providers are vital for enhancing care strategies and improving the quality of life for children with FHS.