Vol. 10, Issue 3, Part E (2024)

Background: A periodontal pocket is a condition characterized by the pathological deepening of the gingival sulcus, accompanied by both hard and soft tissue damage. Complete eradication of subgingival bacteria from infected sites through mechanical means alone is challenging. Microorganisms that persist after scaling and root planing (SRP) can potentially be reduced using microbial agents, enhancing the efficacy of mechanical instrumentation. This approach aims to prevent plaque regeneration, which can otherwise lead to recolonization and the formation of biofilm to assess the impact of using both chlorhexidine and hydrogen peroxide (Glucosite gel) in comparison to chlorhexidine alone on the total viable count within periodontal pockets as a supplementary measure to scaling and root planning.
Methods: This research included 33 periodontal pockets in each set, with depths ranging from 5-6 mm on both sides, employing a split-mouth method. Scaling and root planning were performed solely on the upper side, and the lower right was jaw treated with Glucosite gel, and the left side with chlorhexidine gel. The study evaluated bleeding upon probing and total anaerobic count initially and after 4 weeks. Inter-group comparisons of anaerobic bacterial count between the upper, right, and left sides were documented at baseline and after a month of treatment.
Results: The evidence suggests that the use of a combination CHX-H2O2 gel applied into the periodontal pockets resulted in improved outcomes for both BOP and anaerobic bacterial count compared to SRP alone.
Conclusion: Glucosite can be more effective in reducing bleeding on probing when compared to chlorhexidine gel when used as an adjuvant to scaling and root planning.