Vol. 11, Issue 3, Part E (2025)

Endodontic retreatment is essential when infection persists or recurs in previously treated teeth. Contemporary progress in calcium silicate-based bioceramic sealers have undergone substantial improvements treatment outcomes attributable to their superior biocompatibility, antimicrobial properties, and capability to form a hermetic seal. Their penetration into dentinal tubules, chemical bonding with tooth structure, and alkaline environment help eliminate residual microorganisms and enhance long-term prognosis. Moreover, the single cone (SC) obturation technique, once regarded as inadequate, has regained acceptance when combined with these sealers, achieving high success rates, while the WVC technique continues to offer superior adaptation but with technique-dependent limitations on certain sealers. On the mechanical side, advances in instrumentation, particularly the introduction of oscillating motion systems and heat-treated NiTi files, have improved clinical safety by reducing the risk of instrument fracture and increasing fatigue tolerance. Although studies present mixed findings on their efficiency compared to continuous or adaptive motion systems, the integration of innovative sealing materials with modern instrumentation provides a more predictable, biologically favorable, and efficient approach to retreatment. Nevertheless, further longitudinal clinical investigations are warranted to definitively determine their long-term durability, sealing performance, and clinical advantages of these evolving materials and techniques.