Vol. 11, Issue 4, Part D (2025)

Introduction: Edentulism is among the most prevalent oral health issues affecting humans, and dentures remain the most common treatment option. Natural substances and essential oils have shown great potential as therapeutic agents against oral infections. With growing awareness of the benefits of natural products, they are increasingly being considered as alternatives to synthetic materials. Hence, this study was designed to evaluate and compare the antifungal properties of Aloe vera and probiotics on heat-cured polymethyl methacrylate (PMMA) resin.

Settings and Design: In vitro - experimental study.

Aim: To evaluate and compare the effects of probiotics and Aloe vera extract on the adherence of Candida species to heat-cured denture base resin made of polymethyl methacrylate.

Materials and Methods: A total of specimens were carefully prepared using modeling wax to form discs measuring 10 mm × 10 mm with a thickness of 2 mm. These were divided into four groups:

• Group A: Aloe vera solution
• Group B: Probiotic solution
• Group C: Combination of probiotics and Aloe vera gel in equal proportions
• Group D: Control group

All specimens were immersed in their respective solutions for 15 minutes at 37 °C.

Results: A significant reduction in Candida cell counts on PMMA surfaces was observed following treatment with both probiotic and Aloe vera solutions. Heat-cured denture base materials demonstrated a notable decrease in Candida adhesion after exposure to these natural agents.