Vol. 12, Issue 1, Part A (2026)

Background and objectives: Secondary alveolar bone grafting for treatment of alveolar clefts is an established procedure. Platelet rich plasma, a relatively new concept in maxillofacial surgery, contains a high concentration of growth factors which help faster regeneration of bone across clefts. PRP mixed with autogenous cancellous bone grafts have been used for grafting of alveolar clefts. Several methods of radiography have been employed for quantitative assessment of outcomes of SABG. Universally accepted methods of estimation are yet to be established. The degree to which these estimates agree with each other is open to question.

Methods: PRP mixed with autogenous iliac bone was used as graft material for performing SABG in 12 patients with bilateral clefts. The volume of bone regenerated and percentage of bone support to cleft adjacent teeth was assessed on 3D computerized tomography were analyzed.

Results: Pre-operative and 9 month post-operative height of bone support and percentage coverage of root surface for central incisor and canine adjacent to cleft as assessed on 3D CT were 41.56% ± 15.38 and 86.78% ± 5.78 (central incisor)and 52.38% ± 21.31 and 88.33% ± 8.08 (canine) respectively.

Conclusions and interpretation: Autogenous cancellous bone grafting with PRP is a reliable procedure for SABG in bilateral cleft alveolus patients. 3 Dimensional CBCT’s radiographs give a correct estimate of the three dimensional bone support of cleft adjacent teeth.