Vol. 6, Issue 4, Part D (2020)

Abstract: Melanins are group of pigments found in almost all organisms. In humans and animals, it is chiefly responsible for the color of skin, hair, and eyes. It is synthesized by specific cell called as melanocyte, which are heterogeneous in distribution. Apart from imparting color, it also executes various functions. This review explains the basics of melanin pigment, its biosynthesis, functions, and related pathological conditions in oral cavity. This article also explains the histopathological identification of melanin in tissues including the immunohistochemical markers.